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KMID : 1011420200250030323
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Journal of Korean Ophthalmic Optics Society
2020 Volume.25 No. 3 p.323 ~ p.332
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Analysis of Odd Ratio between Morbidity Type of Circulatory Diseasesand the Prevalence of Ocular Diseases
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Chae Min-Ji
Park Mi-Jung
Kim So-Ra
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Abstract
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Purpose: This study was aimed at determining the correlation between the morbidity of chronic circulatory disease and the prevalence of ocular diseases and at calculating the odds ratio of ocular diseases onset according to the morbidity type of circulatory diseases.
Methods: Raw data of 2017 National Health and Nutrition Survey, which provided ophthalmologic examination results, were used, and only 4,751 subjects in their 40s and above were analyzed. The major chronic circulatory diseases were hypertension, dyslipidemia, stroke, myocardial infarction, and angina pectoris, and major ocular diseases were cataract, glaucoma, macular degeneration, epiretinal membrane, and diabetic retinopathy. The prevalence rate of circulatory diseases was divided into single or multiple morbidity and analyzed by age group. In addition, the correlation and odd ratio of the major ocular diseases were analyzed according to the morbidity type of circulatory diseases.
Results: The prevalence of circulatory diseases increased significantly as subjects’ age increased, and rate of increase was relatively higher in subjects with multiple comorbidity than in those with a single morbidity. Cataract and epiretinal membrane had higher prevalence rates in subjects’ with two or more comorbidity of circulatory disease, while macular degeneration, glaucoma, and diabetic retinopathy had higher prevalence rates in subjects’ with two or fewer morbidity of circulatory disease. Although the odds ratio did not significantly differ among ocular diseases, the highest odds ratio was for cataract in subjects’ with hypertension and myocardial infarction, macular degeneration in subjects’ with dyslipidemia and myocardial infarction, and epiretinal membrane in subjects’ with dyslipidemia, hypertension, and stroke.
Conclusions: From the results, it was revealed that ocular diseases have different correlation according to their single or multiple morbidity of circulatory diseases, and odds ratio greatly varies depending on the combination of circulatory disease, even with the same number of comorbidity. Thus, the development of ocular diseases could be predicted according to the number of type of circulatory disease comorbidity, which could help prevent the onset of ocular diseases.
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KEYWORD
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Chronic circulatory diseases, Morbidity type, Prevalence of ocular diseases, Odd ratio
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